Kaitlyn Wang 17, of San José, CA, won first place and received the $75,000 George D. Yancopoulos Innovator Award, named in honor of the Regeneron President and Chief Scientific Officer, for finding an efficient way to identify certain exoplanets that orbit very closely around their stars. Previous techniques used to detect these ultra-short-period planets required enormous computational power but were not as effective at identifying these planets. Kaitlyn surmounted that problem by creating a special algorithm that runs on cheap hardware and results in much faster and higher-precision findings. Using her research, she says she found the smallest of these planets ever discovered.

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Saathvik Kannan, 17, of Columbia, Missouri, received one of two Regeneron Young Scientist Awards of $50,000 for using biocomputational methods to understand the causes of heightened infectivity in the disease mpox after it reemerged in 2022. Saathvik’s approach, named Bioplex, uses a combination of machine learning and three-dimensional comparative protein modeling to decode structures like those that enable the mpox virus to replicate. This allowed him to identify the mutations in the virus that likely made it more infectious as well as other mutations that could make it resistant to antibiotics. Saathvik believes scientists will also be able to apply Bioplex to future outbreaks of other viruses.

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Teepakorn Keawumdee, 17; Pannathorn Siri, 15; and, Poon Trakultangmun, 18, of Bangkok, Thailand, received the second Regeneron Young Scientist Award of $50,000 for developing an innovative incubation chamber that promotes the survival of the green lacewing insect, a natural predator of the mealybug, a harmful pest. In nature, the green lacewing has a low survival rate, but the team’s new system increased the lacewing’s survival rate five-fold. In field tests, their incubation system was an effective alternative to insecticides and lowered the mealybug population density nearly four-fold.

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Natasha Kulviwat, 16, of Jericho, New York, received the Gordon E. Moore Award of $50,000 for Positive Outcomes for Future Generations for her search for biomarkers to help prevent suicides. By analyzing de-identified brain tissue from 20 people, Natasha measured levels of two proteins, cytokine and claudin-5, and found that neuroinflammation and claudin-5 were increased in the brains of suicide cases. Her work suggests that high levels of the protein claudin-5 could serve as pre-markers for suicide and that certain anti-inflammatory drugs might decrease claudin-5 levels.

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Yuyang Wang, 16, of Shanghai, China, received the Craig R. Barrett Award for Innovation of $10,000 for his development of an inchworm-style stick-climbing robot. This type of robot conventionally has grabbers that allow it to climb over and under obstructions like a caterpillar does, but he added skateboard-like wheels, which allow it to perform better than existing inchworm-style robots when the angle is less than 22°. The hybrid wheel/grabber assembly is novel, and he believes his robot will work well for tasks that are potentially dangerous to humans, such as inspecting damaged high-voltage lines.

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Rishabh Ranjan, 17, and Gopalaniruddh Tadinada, 17, of Louisville, Kentucky, received the H. Robert Horvitz Prize for Fundamental Research of $10,000 for building a custom, automated system to detect gastrointestinal cancer before serious symptoms appear. The team’s system combines robotics and machine learning to analyze blood samples to identify healthy patients, as well as those with pancreatic, colorectal or hepatic cancers, in only three hours at an estimated cost of only $300. Detecting these cancers before they metastasize could make treatment much simpler and more effective.

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Eugene Chen, 16, of Shanghai, China, received the Peggy Scripps Award for Science Communication of $10,000 for his inexpensive energy-saving device that recycles the condensation produced by air conditioners to improve their energy efficiency. His device directs the cooling fan’s airflow to spray the air conditioner’s condensation at its own condenser, lowering its temperature and thus reducing power consumption and improving its energy efficiency. Eugene believes his easy-to-install device can reduce the amount of electricity used by air conditioners by more than 10%.

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