2026 Scholars

Meghana Addanki, Age: 17
McNair Academic High School, New Jersey
Project Title: Efficient Energy Harvesting Using Biomaterials: Fabrication of a ZnO-Modified Eggshell Membrane and Cotton Fabric-Based Piezo-Tribo Hybrid Generator

Aryana Adur, Age: 17
Jericho Senior High School, New York
Project Title: Therapeutic Modulation of a Novel Neuroepithelial Circuit by Larazotide Acetate and Neuregulin-1 Restores Epithelial Barrier Integrity in Food Allergy

Anusha Agarwal, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Multigrid-Inspired Neural Operators for Real-Time Brain Biomechanics Prediction With Spectrally-Aware Learning

Arjun Agarwal, Age: 18
Jesuit High School, Oregon
Project Title: Semisimplifications of α_p-Equivariant GL_n-Modules

Anchita Agrawal, Age: 17
Jericho Senior High School, New York
Project Title: Characterizing Convergent Transcriptomic Impacts of Norepinephrine Across Breast Cancer Grades via “Element AVITI-24”

Avyakt Agrawal, Age: 17
Woodward Academy, Georgia
Project Title: A Novel Adaptive Learning Framework Integrating Item Response Theory, Bayesian Knowledge Tracing and Deep Learning With Confidence-Calibrated Feedback

Lakshmi Agrawal, Age: 18
Stanford University Online High School, California
Project Title: Stormwater Remediation of 6PPD and 6PPD-Quinone Using Citric Acid and Aluminum-Crosslinked Nanocellulose Hydrosponges

Amogh Akella, Age: 17
Westwood High School, Texas
Project Title: Diameter Bounds for Friends-and-Strangers Graphs

Sebastian Rae Alexis, Age: 17
Northwood High School, California
Project Title: A Novel Framework for Stegomalware Detection Using Kolmogorov Complexity

Anish Anand, Age: 18
Palos Verdes Peninsula High School, California
Project Title: A Novel Wireless Charging System for Pacemakers Using 2.4 GHz EM Waves

Aniruth Ananthanarayanan, Age: 18
Texas Academy of Mathematics and Science, Texas
Project Title: Cutting Too Deep: Tracking a Decade of Benign Lung Resections After the Rise of LDCT Cancer Screening

Noah-Duro Christopher Andre, Age: 18
American Heritage School, Florida
Project Title: Isolating, Screening and Identifying Bacteria and Fungi Found Within Mangrove Soil in Florida for Accessible Antimicrobial Natural Products

Rohan Arni, Age: 17
High Technology High School, New Jersey
Project Title: Using Deep Learning for Robust Classification of Fast Radio Bursts

Adhithi Arun, Age: 18
Livingston High School, New Jersey
Project Title: Platelets Promote Multiple Myeloma Cell Survival and Immune Evasion Through Soluble Factors and NK Cell Modulation

Shruti Arun, Age: 18
Cherry Creek High School, Colorado
Project Title: On the Double of an Endymion Algebra in Characteristic 2

Matthew Bace, Age: 18
The Governor’s Academy, Massachusetts
Project Title: Protecting Native Forest Ecosystems: Using AI-Powered Drones for Identifying and Mapping Invasive Insect Populations

Ella Jennings Baker, Age: 18
Spring Valley High School, South Carolina
Project Title: Utilizing the CARRGO Model To Compare the Efficacy of HER2- and EGFR-Targeting CAR-NK Cells on Glioblastoma

Vedant Balani, Age: 17
Jericho Senior High School, New York
Project Title: Hurricane Forecasting Using Comprehensive Multivariable Machine Learning Modeling With Atmospheric Temperatures, Polar Motion and Sunspot Numbers

Pravin Balasingam, Age: 17
Los Gatos High School, California
Project Title: Novel Machine Learning Approach To Identify Brain-Behavior Relationships for Core Autistic Traits

Abhigya Bandugula, Age: 18
Lynbrook High School, California
Project Title: Comparison of RNA-Seq Data From Primary and Recurrent Acute Myeloid Leukemia Patients

Avani Tara Bansal, Age: 18
The Potomac School, Virginia
Project Title: A Novel Pneumatic Silicone Sleeve for Transhumeral Prostheses That Autonomously Regulates and Adjusts to Socket–Limb Pressure To Improve Amputee Comfort

Summerville Beckford, Age: 17
Ossining High School, New York
Project Title: Immersive Virtual Reality Paired With a Stress Mindset Intervention Improves Stress Management in Adolescents

Dhroov Bharatia, Age: 17
Plano Senior High School, Texas
Project Title: AutoMates: Automating With Self-Learning Intelligent Agents

Mishika Bhatia, Age: 17
Rock Canyon High School, Colorado
Project Title: Saw Palmetto-Induced Inhibition of the 5α-Reductase Pathway as a Clinical Treatment for PCOS Symptoms

Allie Blocher, Age: 18
The Lakeside School, Washington
Project Title: Clinical Validation of a Novel $50 Multiple-Pinhole Optometer for Globalizing Vision Testing: Accommodation Bias Drives Dual-Target Innovation

Noelie Roxane Boquet Couderc, Age: 17
Harrison High School, New York
Project Title: Determining if Radioprotection Can Be Enhanced Through the Use of Deinococcus radiodurans MDP and Tardigrada Dsup Protein: Implications for Space Exploration

Srishti Boral, Age: 17
Eastlake High School, Washington
Project Title: Computational Design of Small-Molecule Activators of the AtlA Autolysin To Induce Internal Cell Death in Methicillin-Resistant Staphylococcus aureus

Thanh Can, Age: 17
Jackson Reed High School, DC
Project Title: Measures on Colored Binary Tree Structures and Applications to Tensor Categories

Albert Cao, Age: 18
Centennial High School, Maryland
Project Title: Machine Learning Prediction of On/Off Target-Driven Clinical Adverse Events

Tristan Rei Cao, Age: 18
Stargate School, Colorado
Project Title: Tailoring Quantum Phases via Magneto-Synthesis in a Spin–Orbit-Coupled Trimer Lattice

Abhiram Chalamalasetty, Age: 17
Canyon Crest Academy, California
Project Title: TubercuProbe: A Cross-Attention Graph-Sequence Model for Prioritizing Compound Probes in Mycobacterium tuberculosis

Alexander Ang Chan, Age: 18
Boston Latin School, Massachusetts
Project Title: Gut Microbial Composition and Function Associated With Antidepressant Response: Evidence From a Community-Based Cohort of Older Adults

Tessla Chan, Age: 18
Roslyn High School, New York
Project Title: Investigating PELO as a Novel Synthetic Lethal Target Across Multiple Molecular Subtypes of Gastrointestinal Cancers

Max Charney, Age: 18
Byram Hills High School, New York
Project Title: Harnessing Millions of Consumer Reviews To Reveal Societal Trends at an Unprecedented Scale: Two Proof-of-Concept Studies for a Novel Computational Social Science Approach

Soumik Chemudupati, Age: 17
Liberal Arts and Science Academy, Texas
Project Title: Effectiveness of Amygdala Hijack Threat Cues for Interpretable Phishing Email Detection: A Comparison of Machine Learning, Deep Learning and Large Language Models

Darren Chen, Age: 18
George W. Hewlett High School, New York
Project Title: Watching Others, Withholding Self: How Vicarious Embarrassment Relates to Adolescents’ Online Self-Presentation and Willingness To Share

Hailan Chen, Age: 18
Stuyvesant High School, New York
Project Title: Class IIa Histone Deacetylase HDAC7 Acts as Master Regulator of STAT3 Inflammatory Pathways and HMGCS1 Cholesterol Synthesis Pathways in Reactive Astrocytes

Hayden Chen, Age: 17
Del Norte High School, California
Project Title: A Novel Framework for the Discovery of MAP Kinase-Activated Protein Kinase 2 (MAPKAPK2) Inhibitors Using a Multi-Feature Deep Learning Ensemble

Joshua Chen, Age: 18
Panther Creek High School, North Carolina
Project Title: Exploring Nucleolar Protein 4 (NOL4) as a Novel Biomarker in Neuroendocrine Prostate Cancer Using Single-Cell RNA Sequencing

Rachel Chen, Age: 18
Marlborough School, California
Project Title: The Dual Canonical Basis in the Spin Representation via the Temperley-Lieb Algebra

Shin-En Chen, Age: 17
The King’s Academy, California
Project Title: Characterization of HBV-Host Junction Profile by HBV-Targeted NGS in Urine for Early Detection of Recurrent Hepatocellular Carcinoma and Disease Management

Sophia Chen, Age: 18
Farragut High School, Tennessee
Project Title: Explainable AI-Guided Virtual Experiments Reveal How DNA Sequence Context Shapes Gene Regulation

Vincent Chen, Age: 17
Stuyvesant High School, New York
Project Title: Harnessing Ferroelectric HfO₂-Modified Carbon Nanotube Membranes for Efficient Hydrogen Atom Generation and Transport Toward Sustainable Ammonia Synthesis

Bing Cheng, Age: 18
Trabuco Hills High School, California
Project Title: Increasing Propeller Performance: Investigating the Optimization and Potential of a Novel Propeller Concept Through Computational Fluid Simulation, Experimental Testing Rig and Commercial Drone Integration

Lisa Cheng, Age: 17
Harvard-Westlake School, California
Project Title: Structure-Based D-Peptide α-Synuclein Inhibitor: Tackling Solubility, Specificity and Bioavailability Challenges in Parkinson’s Disease Therapy

Linus Chen-Plotkin, Age: 18
Germantown Friends School, Pennsylvania
Project Title: Predictability and Statistical Memory in Classical Sonatas and Quartets

Ryka Chopra, Age: 17
Mission San Jose High School, California
Project Title: Designing Incentive-Compatible Cooperation for the Global Commons: A Reinforcement Learning-Integrated Mechanism Design Framework for Arctic Conservation

Colin Jie Chu, Age: 18
The Nueva School, California
Project Title: Frequency-Based Parameterization of Semi-Empirical Models for State-of-Health Estimation in Lithium-Ion Batteries in Electric Vehicles

Lindsay Coady, Age: 17
Byram Hills High School, New York
Project Title: The Identification of Anti-Complement Autoantibodies in Schizophrenia: A Novel Gene by Environment Hypothesis of Autoimmunity in Neuropsychiatric Disorders

Mason Corey, Age: 17
Kingsway Regional High School, New Jersey
Project Title: AI-Powered Thermal Fingerprinting: Predicting PLA Tensile Strength Through Schlieren Imaging

Jorge Covarrubias, Age: 17
Harvest Preparatory Academy Yuma, Arizona
Project Title: káktosPatch: Monitoring Necrosis in Carnegiea gigantea (Saguaro Cactus) Using an Engineered Smart Bandage and Mobile Application

Arnav Dagar, Age: 17
Canyon Crest Academy, California
Project Title: ARFSNet–Deep Learning for Amblyopia Risk Factor Screening

Shaunak Dalal, Age: 17
Hershey High School, Pennsylvania
Project Title: Time-Series Deep Learning and Conformal Prediction for Improved Sepsis Diagnosis in Primarily Non-ICU Hospitalized Patients

Rohan Dash, Age: 17
Pine View School, Florida
Project Title: Controllable Multi-Objective Neural Architecture Search via Decision Transformers

Jack D’Cruz, Age: 18
University School, Ohio
Project Title: Immunoproteasome Activation Enhances Melanoma Immunogenicity by Increasing HLA and MAGE-A1 Antigen Presentation

Shaumprovo Debnath, Age: 18
Keystone School, Texas
Project Title: From Thought to Speech: Integrating Low Cost EEGs With AI To Decode Neural Language Signals in Neurologically Intact Non-Verbal Neuromuscular Patients

Jashvi Desai, Age: 18
Yorktown High School, New York
Project Title: Neuroinflammatory Signatures and Compensatory Prefrontal Mechanisms in Long COVID-19: Insights From 7T MRI and Cognitive Modeling

Mythreya Dharani, Age: 18
Bergen County Academies, New Jersey
Project Title: I2-CISSP: An Interpretable Machine Learning Framework for Robust and Practical Prediction of Cisplatin Response in Human Tumors

Bryan Ding, Age: 18
Bergen County Academies, New Jersey
Project Title: Adipocyte-Like Cells as a Novel Source of Myofibroblasts in Pulmonary Fibrosis

Angela Dong, Age: 18
Poolesville High School, Maryland
Project Title: Teaching Robots New Tasks With One Picture (TROP): A Use Case Development Using Edge AI Perception

Andrei Dorobantu, Age: 17
Montgomery Blair High School, Maryland
Project Title: Single-Cell Machine Learning Identifies Functionally Distinct Cytokine Families in Macrophages

Jonathan Du, Age: 18
Los Altos High School, California
Project Title: An Unrestricted Notion of the Finite Factorization Property

Isabel Kelly Duffy, Age: 18
American Heritage School, Florida
Project Title: Laccase-Mediated Degradation of Polyethylene and Polystyrene via Invasion and Ingestion by Pleurotus ostreatus

Patricia Duffy, Age: 18
American Heritage School, Florida
Project Title: Neuroprotective Effects of Astaxanthin in Caenorhabditis elegans Amyotrophic Lateral Sclerosis Models

Leanne Fan, Age: 18
Westview School, California
Project Title: Photobiomodulation on In Vivo and In Vitro Wound Models Under Simulated Microgravity for Future Space Travel

Winston Derek-Xu Fan, Age: 18
West High School, Iowa
Project Title: PsychSPT: A Novel AI System for Mental Health Assessment Using Large Language Models (LLMs)

Nishini Fernando, Age: 18
Dunbar High School, Florida
Project Title: Comprehensive In Vitro Evaluation of Antidiabetic, Antioxidant, Cytotoxic and Wound-Healing Activities of Six Native Plant Species: Prelude to Novel Drug Discovery

Nolan John Francis, Age: 18
Staples High School, Connecticut
Project Title: Vitamin D3 Supplementation Ameliorates Muscle Degeneration Through Calcium Regulation in a Caenorhabditis elegans Model of Duchenne Muscular Dystrophy

Warren Fu, Age: 17
Horace Greeley High School, New York
Project Title: Biophysical and Genomic Drivers of Targeted Therapy Resistance: Analysis of Growth Dynamics in Non-Small Cell Lung Cancer

Fillip Fuňák, Age: 18
North Carolina School of Science and Mathematics, North Carolina
Project Title: Design, Synthesis and Testing of a Novel 3,5-Dimethoxycinnamic Acid-Based Cathepsin C Inhibitor for the Treatment of Inflammatory Bowel Disease

Samanyu Krishna Ganesh, Age: 18
The Westminster Schools, Georgia
Project Title: Characterizing Variations in the Ruelle Zeta Function Under Conformal Perturbations to the Metrics of Negatively Curved Riemannian 2-Manifolds

Yujun Ge, Age: 18
Cerritos High School, California
Project Title: Transforming Assistive Communication: An AI and NLP-Powered Machine Learning Framework for Contextual AAC

Anand Sebastian George, Age: 17
University School of Milwaukee, Wisconsin
Project Title: Prediction of Infection Risk in Multiple Myeloma Patients Treated With Bispecific Antibodies: Neural Network and Ensemble Approaches

Cyrus Ghane, Age: 17
The Harker School, California
Project Title: Toward a Unified Model of the Macaque Cortex With Multi-Scale Spatiotemporal-Neurochemical Integration

Shanice Lashay Gibson, Age: 18
Granbury High School, Texas
Project Title: Design and Validation of a Biomimetic Melanin-Rich Skin Model for Measuring Hydration Retention and Barrier Function Using Low-Cost Sensor Technologies

Scarlet Gitelson, Age: 17
Latin School of Chicago, Illinois
Project Title: Detecting Stellar and Disk Winds Through Absorption Spectroscopy of Black Hole High Mass X-Ray Binary Cygnus X-1

Xavier Gitre, Age: 18
Blacksburg High School, Virginia
Project Title: Partying Parulidae: Interspecific Social Networks of Parulidae Warblers in Active Migratory Passage

Jiaxuan Gong, Age: 18
Northville High School, Michigan
Project Title: Gaussian-Process Generative Model for the QCD Equation of State

Alisa Victoria Gordon, Age: 17
Brooklyn Technical High School, New York
Project Title: The Effects of Acute and Chronic Sleep Deprivation on Metabolic Dysregulation via AgRP Neuronal Activity in the Arcuate Nucleus

Michael Guan, Age: 18
Miami Palmetto Senior High School, Florida
Project Title: Feature-Based Multi-Modal Machine Learning for Diabetes Classification in AI-READI

Andrew Guo, Age: 18
Gwinnett School of Mathematics, Science and Technology, Georgia
Project Title: Investigating the Role of Intrinsic snoRNA Properties on Ribosomal RNA Modification Heterogeneity

Johnny Guo, Age: 18
Choate Rosemary Hall, Connecticut
Project Title: Global Spatiotemporal Analysis of Interactions Between Urban Heat Islands and Heat Waves

Kevin Guo, Age: 17
Horace Greeley High School, New York
Project Title: Development of a SpyTag/SpyCatcher-Based Antibody-siRNA Internalization Assay for High-Throughput Screening

Danika Gupta, Age: 17
The Harker School, California
Project Title: Using AI To Clean Water: Leveraging Large Language Models for Mycoremediation Data Extraction and Modeling

Shivam Gupta, Age: 16
Friendswood High School, Texas
Project Title: Vision AI: A Novel and Cost-Effective Wearable Assistive System for the Visually Impaired Leveraging AI and Machine Vision

Liyang Han, Age: 18
Brookfield Central High School, Wisconsin
Project Title: A Multimodal AI-Powered Diagnostic and Robot-Assisted Rehabilitation System for Parkinson’s Patients

Michael Han, Age: 18
Lexington High School, Massachusetts
Project Title: Improved Bounds for Novelty Games

Karthika Hariprasad, Age: 17
Paul Laurence Dunbar High School, Kentucky
Project Title: A Novel Skin Cancer Detector Using Machine Learning

David Zhang He, Age: 18
Westview School, California
Project Title: An Integrated Analysis of Marine Polyurethane Microplastic Degradation With Genetically Engineered Bacterial Biofilms

Connor Hill, Age: 17
Delta High School, Pennsylvania
Project Title: The Complete Set of Noble Polyhedra

Brendan Hirshorn, Age: 18
Regis High School, New York
Project Title: Explainable Inverse Design of Aluminium and Cobalt Alloys Through Hierarchical Generative Modeling

Daniel Hoberman, Age: 18
Saint Anthony’s High School, New York
Project Title: Mapping the Mind: Quantifying the Relationship Between Access to Healthy Foods and Depression in Southeastern Pennsylvania via Measurement Error-Adjusted Poisson Regression Modeling

Sayeed Hossain, Age: 18
Spackenkill High School, New York
Project Title: Probing Quantum Gravity Signatures: Sensitivity Curves for Novel Interferometer Topologies for the QUEST Experiment Using FINESSE

Neil Xuan Hu, Age: 17
Temple City High School, California
Project Title: Development of an Innovative System To Reduce Ultrafine Particle Ingress Into Vehicle Cabins

Angie Huang, Age: 18
East Ridge High School, Minnesota
Project Title: Entanglement Sudden Death via Repeated Entanglement Swapping

Benson Lu Huang, Age: 17
Half Hollow Hills High School West, New York
Project Title: BLADE: Bioimpedance-Enabled Laparoscopic Articulated Dual-Purpose Endowrist System for Force Sensing and Anomaly Detection in Robotic Surgery

Sophie Katherine Huang, Age: 17
Hackley School, New York
Project Title: Deleting DNA Damage Repair Proteins Exo1, Sgs1, Rad24 and Rad9 Restores Cell Viability in Cdc13-null Candida glabrata

Pax Lu Huybers, Age: 18
Cambridge Rindge & Latin School, Massachusetts
Project Title: Estimating Ocean Wind Speed From Sea Surface Imagery Using Convolutional Neural Networks

Yena Hwang, Age: 18
Saint Anthony’s High School, New York
Project Title: Mechanical Activity of Skeletal Muscle Suppresses Lung Cancer Cell Migration Through Myokine-Mediated Pathways

Liah Igel, Age: 17
Bronx High School of Science, New York
Project Title: Human Cell-Based Assay and Mouse Tissue Analysis To Study FSHR Signaling in Parkinson’s Disease

Michael Iofin, Age: 17
Trinity School, New York
Project Title: Quasiconformal Maps and Random Meromorphic Functions

Anagha Lakshmi Iyer, Age: 17
American Heritage School, Florida
Project Title: A Novel Approach to Sustainable Concrete Engineering: Mechanochemical Activation of Local Waste Materials for CO₂ Reduction

Eli Jacob, Age: 18
Herricks High School, New York
Project Title: Misinformation in Shaping Ethical Attitudes Toward AI-Centered Academic Misconduct via Social Media

Olivia Emma Jacobson, Age: 18
Roslyn High School, New York
Project Title: Parties in the USA: The Impact of Political Party Affiliation Strength and Party Alignment on Perceptions of Bipartisan Candidates

Vasu Jain, Age: 17
Edgemont High School, New York
Project Title: Identification of Chromatin Modification Regulators Implicated in Cancers Through CRISPR Screening

Claire Jiang, Age: 18
Bergen County Academies, New Jersey
Project Title: A Novel In Vitro Cell Culture Model for Juvenile Idiopathic Arthritis

Congyi Lucas Jiang, Age: 17
St. Mark’s School, Massachusetts
Project Title: Design of an Ergonomic Active Spinal Exoskeleton for Lifting Assistance

Billy Jin, Age: 19
Portsmouth Abbey School, Rhode Island
Project Title: GradCAM Analysis Reveals Deep Learning Models Misclassify Benign-Appearing Melanomas Based on Possible Architectural Shortcomings Instead of Misdirection Attention

Everett Jin, Age: 18
St. Mark’s School of Texas, Texas
Project Title: Behavioral Characterization of Zebrafish Seizures for Epilepsy Modeling

Henry Jin, Age: 18
Greenwich High School, Connecticut
Project Title: Bridging the Sim-to-Real Gap in Autonomous Drone Control via Curriculum-Scheduled Domain Randomization

Sophia Yinghan Jin, Age: 17
Stuyvesant High School, New York
Project Title: Coloring-Based Knot Invariants in Projective Space

Serin Jo, Age: 17
Roslyn High School, New York
Project Title: Design of a Lightweight Algorithm for Robust Mass Spectrometry Peak Detection

Addison N. Johnson, Age: 17
Martin Luther King Jr. Magnet High School, Tennessee
Project Title: Octopamine Localization Within the Antennal Sensorimotor System of Drosophila melanogaster

Tyler Cale Johnson, Age: 18
Governor John R. Rogers High School, Washington
Project Title: Shape-Shifting Flight: Exploring the Aerodynamic Performance of a Novel Trailing Edge Variable-Camber Morphing Wing System Implemented in a Flying Wing UAV

Julianna Anastasia Jones, Age: 17
North Carolina School of Science and Mathematics, North Carolina
Project Title: Characterization of Flow in Asymmetric Geometries for Valveless Flow Rectification in Insulin Delivery Microfluidic Systems

Varini Kadakia, Age: 17
Archbishop Mitty High School, California
Project Title: Autonomous Drone-Based System for Outdoor Air Pollution Mitigation

Edward Kang, Age: 17
Bergen County Academies, New Jersey
Project Title: RetinaMind: Convergent In Silico and In Vitro Evidence for the Retina as a Novel Biomarker in the Early Diagnosis of Neurodevelopmental Disorders

Brij Kapadia, Age: 17
Columbia Grammar & Preparatory School, New York
Project Title: Perceived Negative Energy Density Hawking Radiation Near Black Holes: A Tensorial Derivation

Saurish Kapoor, Age: 17
Princeton High School, New Jersey
Project Title: A Deep Learning Approach for an Early and Non-Invasive Diagnosis of Cardiovascular Disease in Cattle Using Retinal Fundal Images

Khushi Karthikeyan, Age: 18
Ardsley High School, New York
Project Title: The Supermassive Problem: Probing Potential Stellar Formation Pathways of Intermediate-Mass Black Holes

Maxwell Kesselheim, Age: 18
The Roxbury Latin School, Massachusetts
Project Title: Framing Policy Through Humor: A Computational Analysis of Reddit Memes

Lucienne Sophie Keyoung, Age: 18
Manhasset High School, New York
Project Title: Tunable Morphology of Zero-Waste Cellulose Nanofiber Hydrogels via a Novel Gelatin-Mediated Ice Inhibition Mechanism for Sustainable Agriculture and Water Remediation

Alex Kidangathazhe, Age: 17
Stillwater High School, Oklahoma
Project Title: Transforming Natural Phenolics Into Bactericidal Therapeutics Using a Systems-Guided Stress Response Framework

Eashan Kosaraju, Age: 17
Solon High School, Ohio
Project Title: A Data-Driven Framework for Quantifying County-Level Structural Disadvantage and Disparities in Premature Mortality

Mythili Venkata Kota, Age: 17
McNair Academic High School, New Jersey
Project Title: Engineering a Novel Electrochemical Biosensor Using a Self-Healing ZnO Quantum Dot Matrix With MIP Technology for Lysozyme Detection

Soneesh Kothagundla, Age: 17
South Forsyth High School, Georgia
Project Title: Hard To Reach or Hardly Reached? Investigating Use of Lung Cancer Screening Among Eligible U.S. Adults Receiving Other Cancer Screenings

Aaron Eli Krasinski, Age: 18
Bronx High School of Science, New York
Project Title: A Novel Deep Learning Approach to the Health Crisis of Industrial Production in Space: Neural Network Classification and Glymphatic Biomarker Analysis of Spaceflight-Associated Neuro-Ocular Syndrome for Pre-Flight Crew Screening

Rushil Kukreja, Age: 16
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Preparing for the Next Carrington: Spatiotemporal Agent-Based Modeling for Safeguarding Satellite Infrastructure Under Extreme Space Weather Disturbances

Aiden Kwon, Age: 18
Palos Verdes Peninsula High School, California
Project Title: Revolutionizing Turbulence Studies: Novel Low-Cost Zero Mean-Flow Chamber Design and Computational Analysis of Reynolds Stress Tensor

Sam Land, Age: 17
Bronx High School of Science, New York
Project Title: Novel Characterization of COMT Gene Polymorphism Effects on Resting-State fMRI Network Segregation: A Breakthrough for Personalized Mental Health Treatment

Diego Benjamin Landeros, Age: 18
Lane Technical High School, Illinois
Project Title: Targeted Nitroisoxazole-Based GPX4 Inhibitor Drug Conjugate for Ferroptosis Induction in Chemoresistant Tumors

Darren Lau, Age: 18
Academy at the Lakes, Florida
Project Title: AuRING: A Novel Augmented Reality Intraoperative Neurosurgical System Using a Dual Discriminator Bayesian-Structural Similarity Generative Adversarial Network (D²BS²GAN) for Real-Time Brain Shift Compensation

Eun Jae Lee, Age: 18
Peachtree Ridge High School, Georgia
Project Title: Silent Signals: Boronic Acids Quench E. coli Quorum Sensing

Franklin Lee, Age: 17
Jericho Senior High School, New York
Project Title: Dual-Pathway Fusion of EHRs and Knowledge Graphs for Predicting Unseen Drug-Drug Interactions

Jaeho Lee, Age: 18
Spring Branch Academic Institute, Texas
Project Title: Affine Group of Integers Modulo n, Conjugacy Classes and Representations

Jooa Zoe Lee, Age: 18
Lexington High School, Massachusetts
Project Title: Multi-Omics Identification of SDHA Amplification as a Non-Invasive Biomarker in Saliva-Derived ctDNA From Non-Smoker Lung Cancer Patients

Madeline R. Levorson, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Novel Antimicrobial Treatments Designed With Discovered Lytic Bacteriophages Evaluated Through a Rapid Screening Protocol and an In Vivo Galleria mellonella System

Caroline Li, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Improving the Detection Sensitivity of Calcium Transients in Densely Labeled Neuronal Tissue Through Pinhole Illumination: A Low-Cost Approach

Ella Li, Age: 18
Saratoga High School, California
Project Title: Developing a High-Resolution, Cost-Effective, Saliva-Based HLA Typing Method With Long-Range PCR To Detect Autoimmune Disease Susceptibility

Mary Meijia Li, Age: 17
Hume-Fogg Academic High School, Tennessee
Project Title: Linking Early Life Adversity to Epigenetic Change: A Meta-Analysis of DNA Methylation as a Molecular Memory of Childhood Trauma

Sophia Li, Age: 18
John L. Miller Great Neck North High School, New York
Project Title: Closing the Shade Gap: Advancing Environmental Equity Through Understanding Tree Canopy Disparities in Redlined Communities With i-Tree

Leo Lian, Age: 18
Lake Washington High School, Washington
Project Title: Bridging the Justice Gap for Pro Se Civil Rights Plaintiffs: AI-Assisted Complaint Drafting Guided by Analysis of 3,750 Federal Cases

Frances Liang, Age: 17
The Nueva School, California
Project Title: PLI-Analyzer: A Novel Platform for Quantitative Assessment of Structural and Biological Accuracy in AI-Predicted Protein-Protein Complexes

Sophia Liang, Age: 17
Centennial High School, Maryland
Project Title: Pharmacologic Soluble Guanylate Cyclase Activation for Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells: Implications for Wet Age-Related Macular Degeneration

Aaron Lin, Age: 17
Ladue Horton Watkins High School, Missouri
Project Title: The Geometry of a Counting Formula for Deformations of the Braid Arrangement

Helen Lin, Age: 18
Bronx High School of Science, New York
Project Title: Human Intervertebral Disc Degeneration, Sex and Aging Increase Alpha-1 Antitrypsin Expression in Intervertebral Discs

Jia Tong Lin, Age: 17
Yorba Linda High School, California
Project Title: Walking Assistant: Automated Exoskeleton With Flexible-Rigid Coupled Hip Joint and Spine

Matthew Lin, Age: 17
Roslyn High School, New York
Project Title: Using Bayesian Optimization To Design Conductive PEO-Based Mixed-Graft Block Copolymers

Christina Xinyi Liu, Age: 18
The Lakeside School, Washington
Project Title: Applying Explainable AI To Understand How Stellar and Planetary Parameters Impact Exoplanet Habitability

Elaine Liu, Age: 17
Syosset High School, New York
Project Title: The Effects of Apology Strategies on the Spread and Intensity of Cancel Culture Incidents

Geoffrey Liu, Age: 18
Glenda Dawson High School, Texas
Project Title: A Gamified Go/No-Go Paradigm for the Epilepsy Monitoring Unit

Grace Chenxin Liu, Age: 17
Syosset High School, New York
Project Title: Evaluating Gender Differences in the Effects of Ambiguity and Misperception on Entrepreneurship in Three Business Development Stages: A Panel Data Analysis

Isabel Shuan Liu, Age: 17
Liberal Arts and Science Academy, Texas
Project Title: A Novel Biomarker-Integrated Machine Learning Model in Chemotherapy-Induced Cardiotoxicity Risk Prediction

Jiayi Michael Liu, Age: 18
The Loomis-Chaffee School, Connecticut
Project Title: Differentiation and Functional Evaluation of Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Cerebral Organoids To Model the AUTS2 Variant

Kevin Liu, Age: 17
Jericho Senior High School, New York
Project Title: Integrative Structural Modeling and Molecular Dynamics Simulations Reveal Novel Insights Into Autism SORCS3 Missense Mutations

Louis Liu, Age: 17
University High School, Arizona
Project Title: FallPoint: Fall Detection With 4D mmWave Radar Using PointNet and a Recurrent Neural Network

Mason Liu, Age: 18
Thomas S. Wootton High School, Maryland
Project Title: Developing a Novel BMS-986158 and Flavopiridol Combination Therapy for Treating Pediatric Brain Tumors

Anthony Low, Age: 17
Arnold O. Beckman High School, California
Project Title: A Novel 0D/2D Composite Phase Change Material for Thermal Management in High-Performance Computing

Lauren Low, Age: 18
Northwood High School, California
Project Title: A Novel Sparse-IMU Convolutional Neural Network for Real-Time Hip Kinematics in Exoskeleton-Augmented Gait

Ella Lu, Age: 17
North Carolina School of Science and Mathematics, North Carolina
Project Title: Compositional Analysis of Visual Art Structure

Kevin Lu, Age: 17
Bellarmine College Preparatory School, California
Project Title: AEGIS: Security Sandboxing Meets Mechanistic Interpretability To Defend Against Prompt Injection Attacks

Samuel Lu, Age: 18
Rowland Hall, Utah
Project Title: RPE Senescence and Age-Related Macular Degeneration: An Investigation of the Small GTPase ARF6 as a Potential Target for AMD Pathogenesis

Frank Lucci, Age: 18
BASIS San Antonio Shavano Campus, Texas
Project Title: SubArc: An Inexpensive, High Resolution, Open Source, Absolute Magnetic Rotary Encoder

Kai Lum, Age: 17
BASIS Independent Fremont, California
Project Title: Extremal Structural Results for Feedback Arc Sets and Graph Inversions

Anna Luo, Age: 17
Canyon Crest Academy, California
Project Title: Allelopathic Effects of Cynara cardunculus on Native Coastal Sage Scrub Species

Emma Luo, Age: 17
Northville High School, Michigan
Project Title: Steep Monetary Delay Discounting in Opioid Use Disorder: Application of the Rachlin Hyperbolic Model

Aliyah Majeed-Hall, Age: 18
The Potomac School, Virginia
Project Title: TRACE-Stem: A ²²²Rn-Calibrated Mechanistic Model of Methane (CH₄) and Carbon Dioxide (CO₂) Transport in Tree Stems

Rhea Malhotra, Age: 18
Stuyvesant High School, New York
Project Title: Identifying Therapeutic Gene Targets for Cataract and Glaucoma

Elias Malionek, Age: 18
Briarcliff High School, New York
Project Title: The Effects of Education of Interpersonal Relationships and Positive Masculinity in a Group Environment Led by a Same-Sex Peer With Adolescent Males on Depression, Self-Esteem and Ideologies of Masculinity

Finnegan McGill, Age: 18
Tanque Verde High School, Arizona
Project Title: A-BiRD: An Automated Bird Recognition Device for Acoustic Monitoring and Conservation

Alexander Miller, Age: 17
Woodbridge High School, California
Project Title: Universal Quantum Error Mitigation via Random Inverse Depolarizing Approximation

Yashnil Mohanty, Age: 17
Westmont High School, California
Project Title: Physics-Guided Neural Forecasts of Nearshore Harmful Algal Blooms in the California Current System

Benjamin Drew Moses, Age: 18
Paul D. Schreiber High School, New York
Project Title: Symptoms of Depression and Anxiety Among Survivors of Childhood, Adolescent and Young Adult (CAYA) Cancer

Natalie Muro, Age: 18
William J. Palmer High School, Colorado
Project Title: A Novel Field-Based Approach to Reducing Harmful Algal Blooms in Freshwater Ecosystems

Seth Jacob Nabat, Age: 18
William Howard Taft High School, California
Project Title: Learning Broken Symmetries With Approximate Invariance: A Novel Dual-Subnetwork Approach to Classifying Particle Collision Events

Ananya Gulur Nagendra, Age: 18
Plano East Senior High School, Texas
Project Title: Utilizing Ants To Mitigate MSW Landfill-Generated Methane Production Through Novel Aerobic Digester System for Anthropogenic Food Waste Decomposition

Siddharth Nair, Age: 17
Yorktown High School, New York
Project Title: Large-Scale Plastic Detection Pipeline via Machine Learning-Augmented Remote Sensing

Nived Nandakumar, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: A Closed-Loop Deep Generative Model for the Inverse Design of Radiation-Resistant Polymers

Sharanya Sanjay Natarajan, Age: 18
Edgewood Junior/Senior High School, Florida
Project Title: An Integrated Detection and Delivery System To Abate Contaminants in Water Bodies

Paarth Nawani, Age: 18
Cupertino High School, California
Project Title: A Low-Cost Non-Mydratic Retinal Imaging System With a Multistage Deep Learning Pipeline for Automated Screening of Glaucoma

Eleanor Nayden, Age: 18
Princeton High School, New Jersey
Project Title: Impact of Political Allegiance on H-1B Visa Acceptances to the U.S.: An Analysis of the Relationship Between UNGA Voting Alignment and H-1B Visa Acceptances to the United States

Bach Ngo, Age: 17
Frazer School, Florida
Project Title: Hexaïssa: Deep Strategic AI for Complex Real-World Decision Making

Max Hung Nguyen, Age: 17
Leland High School, California
Project Title: Star2Planet: Decoding and Predicting the Stellar Signatures of Planet Formation

Lindsey Liang Niu, Age: 17
Monta Vista High School, California
Project Title: Developing PDMS Microfluidic Sensors for Precise Micro Blood Flow Measurement To Advance Cardiovascular Diagnosis in Low-Income Regions

Olivia Grace Nostro, Age: 17
Brooklyn Technical High School, New York
Project Title: Effects of Non-Pharmacological Treatments on Seizure Duration in Bang-Sensitive Drosophila melanogaster Mutants

Suzuko Ohshima, Age: 18
North Hollywood High School, California
Project Title: Biophysical Characterization of SUN2-Pro-Macrobody Interactions Elucidates Multimerization Dynamics and Complex Stability

Willa Olson, Age: 17
Yorktown High School, New York
Project Title: The Effect of Endocrine-Disrupting Chemicals on the Social Behaviors and Testosterone Levels of the North American River Otter (Lontra canadensis)

Viktor Osadsky, Age: 18
Exeter High School, New Hampshire
Project Title: Scoring Radiography Collimation: Quantifying Background Impact Using Neural Networks

Sritej Sai Padmanabhan, Age: 17
North Allegheny Senior High School, Pennsylvania
Project Title: Linking Goals to Learning: A Novel Goal-Inclusive Kalman Filter Framework Reveals That Goal Uncertainty Attenuates Sensorimotor Adaptation

Suhani Pahuja, Age: 17
Monta Vista High School, California
Project Title: Long-Term Cardiovascular and Mortality Risk in Patients With Preexisting Arrhythmia Post SARS-CoV-2 Infection

Aarthi M. Palaniappan, Age: 17
Herricks High School, New York
Project Title: Elucidating the Protective Role of Wnt4 Signaling and Gene Suppression in Modulating Fibrotic and Calcific Pathways in Calcific Aortic Valve Disease

Rayhan Papar, Age: 18
The Woodlands College Park High School, Texas
Project Title: Sim-to-Real for Autonomous Tumor Resection via Minimally Invasive Robotics

Lila Lewis Papavasiliou, Age: 18
Thousand Oaks High School, California
Project Title: Identifying the Existence of Unconscious Gender Bias in the Perception of Political Speakers Using EEG

Medha Pappula, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Identifying Underlying Brain Connections in Pediatric ADHD: A Pathway to Early Diagnosis and Reduced Secondary Effects

Kaya Parikh, Age: 17
Hunter College High School, New York
Project Title: Ozempic® and Counterfeit Ozempic in Novel Triple-Readout Drosophila Model With Type-2 Diabetes and Obesity

Natalie Partridge, Age: 18
Ossining High School, New York
Project Title: Reading Interventions Foster Prosocial Behavior Development in Young Children

Siddharth Pasari, Age: 17
Hunter College High School, New York
Project Title: Development of N-glycan Microarrays as Sensors for Glycan Binders

Arnav Pemmaraju, Age: 18
William A. Shine Great Neck South High School, New York
Project Title: CRE-LogicSim: A Surrogate Modeling Framework for Interpreting Cis-Regulatory Element Function in Deep Sequence Models

Aashritha Penumudi, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: A Novel Approach to Understanding the Structural Basis of Ribosome Stalling by AMD1 and Cellular Arresting Peptides

Zeviel Pineda, Age: 18
Veterans Memorial Early College High School, Texas
Project Title: Accelerating Whole-Brain Axonal Mapping Through Supervised Machine Learning and Proof of Concept in a Familial Alzheimer’s Disease Mouse Model

Karthik Prasad, Age: 18
Illinois Math and Science Academy, Illinois
Project Title: On Yetter-Drinfeld Modules Over the Pansera Algebras

Cynthia Qian, Age: 18
Jericho Senior High School, New York
Project Title: Computational Discovery of Marine Plastic-Degrading Enzymes Enhanced by Deep Eutectic Solvents

Vallabh Ramesh, Age: 18
duPont Manual Magnet High School, Kentucky
Project Title: Next-Gen Smart Materials: Thermo-Responsive and Conductive 3D Printable Polymer Gels for Diverse Applications

Elijah Renner, Age: 17
Thetford Academy, Vermont
Project Title: Pathformer: Large Language Models for Automated Billing Code Assignment in Multi-Institutional Pathology Reports

Ryan Sean Rezaei, Age: 18
Canyon Crest Academy, California
Project Title: Omni-Prot: Unifying Protein Function Prediction With PLM-Centric Fusion

Azimullah Rifai, Age: 18
Poolesville High School, Maryland
Project Title: Identification and Functional Validation of Single-Cell Resolved Myeloid Reprogramming Drivers in the Prostate Cancer Bone Metastatic Niche

Emily Ann Salemo, Age: 17
Harrison High School, New York
Project Title: The Effect of α-Tocopherol on Locomotor Ability of The Drosophila melanogaster Mutant for Glutathione S-Transferase Theta 3

Shanza Sami, Age: 17
West High School, Iowa
Project Title: SPECO: A Novel Multiparametric Methane Forecasting and Mitigation System Using Quantum Long Short-Term Memory and Sonophotoelectrochemical Oxidation

Akshat Santhana Gopalan, Age: 18
John P. Stevens High School, New Jersey
Project Title: TARGen: Novel Target-Aware Deep-Generative Framework for De Novo Therapeutic Antibody Design Develops Antibodies Targeting the Dark Kinome

Moitri Santra, Age: 16
Oviedo High School, Florida
Project Title: Development of an Industrially Viable Neutral pH Oxytetracycline Nanocarrier for Citrus and Stone Fruit Disease Management

Samuel Siddhartha Sastry, Age: 18
The College Preparatory School, California
Project Title: Folding and Reconfiguration of DNA Origami Book Structures

Aditya Sengupta, Age: 17
Bellevue High School, Washington
Project Title: ForeCAT: Advancing Clear Air Turbulence Prediction for Aviation Safety With Atmospheric Physics-Informed Neural Networks and Spatiotemporal Weather Data

Noah Michael Senzon, Age: 18
North Carolina School of Science and Mathematics, North Carolina
Project Title: Evaluating Kudzu (Pueraria montana) as a Sustainable Fiber for Thermal Insulation

Ananya Shah, Age: 17
Edgemont High School, New York
Project Title: A Comparison of Precinct and District Voting Data Using Persistent Homology To Identify Gerrymandering in North Carolina

Ashka Shah, Age: 17
Jericho Senior High School, New York
Project Title: Selective Dual Inhibition of β-Catenin in Wnt-Driven Cancers via Gid8-Assisted Translocation and a Precision Peptide-Based Gene Therapy

Nikhil Shah, Age: 18
Syosset High School, New York
Project Title: Examining the Impact of the Federal Sentencing Guidelines on Racial Disparities in Federal Sentencing

Iris Shen, Age: 17
The Woodlands College Park High School, Texas
Project Title: Assessing Marine Bivalves as Novel Invertebrate Models for Targeting Anti-Apoptotic BCL-2 Family Proteins in Blood Cancer: The In Vivo Effects of Ursolic Acid and Gossypol Acetic Acid on Tumor Cells in Mercenaria mercenaria

Lily Shi, Age: 17
The Harker School, California
Project Title: Enhancing Medical Explainability in Deep Learning for Age-Related Macular Degeneration Diagnosis

Aditya Shivakumar, Age: 18
The Harker School, California
Project Title: Ultra Low-Cost, Field-Deployable Arsenic(V) Detection and Adaptive Hotspot Mapping With Methylene Blue-Gold Nanoparticle Colorimetry and Smartphone Spectroscopy

Rohan Shivakumar, Age: 17
Viewpoint School, California
Project Title: A Novel Early-Warning Signal of Wildfire Spread Using Vegetation Stress at the Edge of Fire Fronts

Shawnak Shivakumar, Age: 17
Menlo Atherton High School, California
Project Title: Drugging the Undruggable: AI-Enabled Discovery of a Novel Cryptic Pocket and Inhibitors in Oncogenic eIF4E

Elizabeth Lilian Singh, Age: 17
Westlake High School, New York
Project Title: A Novel Epigenetic Pathway to Reversing Pulmonary Arterial Hypertension? Investigating the Regulating Role of UHRF1 in Smooth Muscle Cells

Ruhaan Singh, Age: 17
Farragut High School, Tennessee
Project Title: Utilizing a Temporal Sequence Transformer To Effectively Forecast Streamflow Across Diverse Hydroclimatic Regions in the United States

Indira Rajyalakshmi Sivaraj, Age: 16
Elk River Area Senior High School, Minnesota
Project Title: Uncovering Atomic-Level Insights in Metabolic Drug-Target Receptors Using Interpretable Machine Learning

Sebastien Sobeih, Age: 18
Phillips Exeter Academy, New Hampshire
Project Title: The Cross-Dependent PDFS Model and Its Application: Smagorinsky-LES Inspired Subgrid-Scale Models and Multiscale Cascade for Transfer of “Volatile Energy” Within Financial Markets

Dhruvika M. Solanki, Age: 17
Morgantown High School, West Virginia
Project Title: Theory-Trained Neural Networks for Robust Arrhythmia Classification

Kian Daniel Soleymani, Age: 17
John L. Miller Great Neck North High School, New York
Project Title: AI-Powered Conversational Tool for Early Stage Cognitive Decline

Alexis Solomon, Age: 17
Columbia Grammar & Preparatory School, New York
Project Title: The Role of Adolescent Sports Participation in Behaviors and Social Functioning in Young Adulthood

Andy Song, Age: 19
Phillips Exeter Academy, New Hampshire
Project Title: Investigating the Molecular Mechanisms of TCERG1 SNP rs79727797 in Modifying Huntington’s Disease Onset

Frederick Song, Age: 17
Solon High School, Ohio
Project Title: Trends in the Use of Reirradiation for Second Primary Breast Cancer

Siddharth Sridharan, Age: 18
Little Rock Central High School, Arkansas
Project Title: The Neurobiology of Voluntary Exercise: A Novel Approach To Alleviate Chemobrain by Promoting Hippocampal Neurogenesis

Cole Jacob Stern, Age: 17
John F. Kennedy High School, New York
Project Title: Investigating the September 29, 2023, Tri-State Flooding Event: A WRF-Based Analysis of Tropical Storm Ophelia, Elevated Sea Surface Temperatures and Their Role in Enhancing Extreme Rainfall

Uma Maya Sthanu, Age: 17
Westwood High School, Texas
Project Title: Glia-Neuron GPCR Signaling as a Therapeutic Route to Axon Regeneration: cAMP-PKA Activation Elevates Excitability and Regrowth in Neurons

Emma Elise Su, Age: 17
Herricks High School, New York
Project Title: Developing a Novel Adaptive Tuning Module for Real-Time Frequency Correction in Radiofrequency Coils During Concurrent TMS-fMRI

Kevin William Sun, Age: 17
Andover High School, Massachusetts
Project Title: Printing 2D MXene-Based Chipless Radio Frequency Identification Tags To Enable Plastic Waste Sorting for Recycling

Rebekah Rose Switzer, Age: 18
North Carolina School of Science and Mathematics, North Carolina
Project Title: Tannic Acid-Loaded pHEMA-Quaternary Chitosan Hydrogels for Use as Antimicrobial Contact Lenses

Eric H. Tang, Age: 18
Little Rock Central High School, Arkansas
Project Title: Comparison of the Presence of Heavy Metal Resistance Genes in Salmonella enterica and Their Association With Antibiotic Resistance

Kaavya Tatavarty, Age: 17
Henry M. Gunn High School, California
Project Title: Personalized Cloud-Based Semg-to-Haptic System To Enable Long Distance Communication for Usher Syndrome

Cooper Taylor, Age: 18
Greenwich Country Day School, Connecticut
Project Title: Lightweight Modular Dual-Tilt VTOL UAV: Design, Validation and Long-Endurance Performance

Hunter James Taylor, Age: 18
Dutch Fork High School, South Carolina
Project Title: The Implementation of Ostracods in Aquaculture Greenwater Systems

Abigail Thomas, Age: 17
Herricks High School, New York
Project Title: Examining the Pathway of Rab8-Mediated Trafficking of GluA1-AMPARs in Response to In Vitro Chemical LTP Induction in Wildtype and Lrrk^2G2019S Striatal and Cortical Neurons

Serina Tomioka, Age: 17
Ardsley High School, New York
Project Title: Characterizing the Spatial Dynamics of CD44 and Amyloid-Beta Plaques in Human Alzheimer’s Disease Brain

Uyen Tran, Age: 19
Bergen County Academies, New Jersey
Project Title: Effect of Tamoxifen and 17-β-Estradiol on Lung Adenocarcinoma Proliferation: What Do We Know About the Role of Sex Hormones in Lung Cancer?

Zoe Tran, Age: 17
Laguna Beach High School, California
Project Title: Development of a Novel Co-Expression-Dependent Direct Protein Interaction Mapping Method

Maya Julia Trutschl, Age: 18
Caddo Parish Magnet High School, Louisiana
Project Title: Automated Prediction and Prevention of Pressure Injuries Using Machine Learning and Thermal Sensing: A Clinical Validation Study

Sam Tummala, Age: 17
Chantilly High School, Virginia
Project Title: From Waste to Worth: Transforming Resistant Starches From Waste Rice Into a Single-Use Plastic Alternative and Controlled-Release Organic Fertilizer

Atharva Tyagi, Age: 18
Woodbridge Academy Magnet School, New Jersey
Project Title: From Mutation to Cure: A Prime Editing Approach to Universal Genetic Rescue in Familial Hypercholesterolemia

Aadhi Umamageswaran, Age: 17
West High School, Utah
Project Title: Visualizing Animal Vocalizations for Species Identification

Luis Vidal, Age: 18
Arkansas School for Mathematics, Sciences & the Arts, Arkansas
Project Title: Designing Substrates To Test HELB as a Potential Therapeutic Agent Against Glioma and Colon Adenocarcinoma

Natalie Viderman, Age: 17
Hunter College High School, New York
Project Title: Hypoxia as a Novel and Non-Invasive Experimental Treatment Model for Congenital Dsyerythropoietic Anemia and Rare Erythroid Diseases

Emily Walch, Age: 18
Pelham Memorial High School, New York
Project Title: Testing a Domain-Specific Impact of English Language Cognitive Test Bias in Spanish Speakers in the United States

Alexander Wang, Age: 18
Millburn High School, New Jersey
Project Title: Bounds on the Number of Edges in Visibility Hypergraphs

Angela Wang, Age: 17
University School of Milwaukee, Wisconsin
Project Title: A Novel CNN-Based Approach for Early Alzheimer’s Prediction Using Linkage Disequilibrium Matrices From APOE Genetic Data

Brady Wang, Age: 18
Horace Greeley High School, New York
Project Title: Generation of Antibody Oligonucleotide Conjugates Using a Novel Conjugation Technology

Julang Wang, Age: 18
Friends Academy, New York
Project Title: Localized Metaresonators for Mid-Wave Infrared Spatial Light Modulators

Leon Wang, Age: 17
King School, Connecticut
Project Title: Repurposing Idiopathic Pulmonary Fibrosis Drugs To Treat Vascular Alzheimer’s Dementia: A Safe, Effective and Accessible Approach to Alzheimer’s Treatment

Lucas (Zihe) Wang, Age: 17
Los Gatos High School, California
Project Title: InnoColor Edge: A Real-Time Wearable System With Distilled Vision Transformer-Guided Recoloring for Color Vision Deficiency

Yanchen Wang, Age: 17
St. Francis Preparatory School, New York
Project Title: Characteristics and Risk Factors of Anomalous Sleep Experience (Sleep Paralysis) in American Adolescents

Otto Watson-Brown, Age: 17
Martin Luther King Jr. Magnet High School, Tennessee
Project Title: Using Foldit To Design Novel KNa1.2 (Slick) Channel Inhibitors

Haodong Wei, Age: 18
Cranbrook Kingswood School, Michigan
Project Title: LLM-Powered, Chain of Action (CoA)-Based, Multi-Agent Collaboration for Hexapod-Drone Systems

Mary Wei, Age: 18
Evergreen Valley High School, California
Project Title: A Fast and Accurate Method for Numerical Integration of Bandwidth-Limited Signals

Huxley Westemeier, Age: 18
St. Paul Academy & Summit School, Minnesota
Project Title: Integrity: Generalized Artificial Image Classification With Noise Domain Localization

Nolan H. Woo, Age: 18
Saratoga High School, California
Project Title: A Comparative Study of AI and Human Programming on Environmental Sustainability

Brad Wu, Age: 17
Arizona College Preparatory High School, Arizona
Project Title: A Brain-Computer Interface-Driven Forearm Exoskeleton With Adaptive Neuroregulation-Based Feedback for Stroke Rehabilitation

Flora Rain Wu, Age: 17
Guilderland Central High School, New York
Project Title: The Impact of Maternal Risk Factors and Drinking Water Contaminants on Cyanotic Congenital Heart Defects

Xi Zhen Wu, Age: 18
Bronx High School of Science, New York
Project Title: Exploring the Potential of Inhaled Tadalafil Liposomes for Pulmonary Arterial Hypertension

Anfeng Xie, Age: 18
St. Paul’s School, New Hampshire
Project Title: An Energy-Generating and Power-Storing Seashell: An Innovative Attempt To Increase Power Output While Lowering Cost

Arianna Aisi Xie, Age: 17
Shanghai High School International Division, China
Project Title: Enhancing Base-Editing Efficiency by DNA Gap Induction

Henry Xie, Age: 17
Westview High School, Oregon
Project Title: Distilling Empathy From Large Language Models

Sonja Xie, Age: 17
Scarsdale High School, New York
Project Title: Neurite Degeneration Induced by UK-5099 Inhibition of the Mitochondrial Pyruvate Carrier Reveals Metabolic Thresholds for Neuronal Integrity

Keith Xin, Age: 18
Whitney Young Magnet High School, Illinois
Project Title: High-Capacity Al³⁺/Fe³⁺-Crosslinked Nanocellulose Hydrogels for Arsenite Removal: A Zero-Waste Approach to Water Remediation

Tina Shuxin Xing, Age: 17
Ward Melville High School, New York
Project Title: Carbon-Aware Reserve Allocation and Checkpoint Scheduling for GPU Sustainability

Jenny Zhang Xu, Age: 18
Fairview High School, Colorado
Project Title: CaraG Nanoparticle, a Novel CRISPR/SaCas9 Delivery Vehicle To Disrupt ANGPTL3 and PCSK9 Genes for Hypercholesterolemia Treatment

Jerry Xu, Age: 17
Lexington High School, Massachusetts
Project Title: A Unified Protein Embedding Model With Local and Global Structural Sensitivity

Ryan Xu, Age: 17
Plano West Senior High School, Texas
Project Title: LibAssembler: A Neural Framework for Library-Constrained Reconstruction of 3D Part Assemblies From a Single 2D Image

Jonathan Yan, Age: 18
Sage Hill School, California
Project Title: Bioinformatic Analysis of Metastasis-Associated Metabolic Landscape Reveals an Oncogenic Role for the Transsulfuration Pathway

Sophia Yan, Age: 17
Newton South High School, Massachusetts
Project Title: Mapping Enhancer-Gene Interactions in the Human Brain Reveals Reduced Use of Enhancers for Synaptic Genes in Schizophrenia

Berkay Yilmaz, Age: 17
John P. Stevens High School, New Jersey
Project Title: DNA Chalk: Calcium Carbonate-Functionalized DNA Tensegrity Triangle Crystals for Targeted Drug Delivery

Alyssa Yu, Age: 17
Poolesville High School, Maryland
Project Title: When Epidemics Meet: Understanding Spatiotemporal Interactions of Two Pathogens on Metapopulation Networks via Reaction-Diffusion Dynamics

Amy Yu, Age: 17
White Station High School, Tennessee
Project Title: Exploring the Power-Performance Balance: GPU Frequency Scaling in AI Workloads

Qiuen Yu, Age: 18
The Lawrenceville School, New Jersey
Project Title: Advancing Phytoremediation of PFAS in Biosolids: Soil Condition Optimization and Nutrient Preservation

Tommy Yuan, Age: 18
Jericho Senior High School, New York
Project Title: A Genetic Algorithm Approach to Automated Strategy Acquisition in 2048

Alex Zhang, Age: 18
Cate School, California
Project Title: Prometheus: A Recursively Self-Improving NAS System

Celine Zhang, Age: 18
Phillips Exeter Academy, New Hampshire
Project Title: Designing Zero-Knowledge Proofs for Agent Motion Planning

Claire Zhang, Age: 17
Brentwood High School, Tennessee
Project Title: Tardigrades’ Cytoplasmic Abundant Heat-Soluble Proteins Serve as Membrane Protectors During Dehydration

Evan Zhang, Age: 17
The Harker School, California
Project Title: Self-Sensing Hydraulically Amplified Self-Healing Electrostatic Artificial Muscles With AI-Driven Control for Cardiac Assist

Kelly J. Zhang, Age: 18
Polytechnic School, California
Project Title: Sentinel-2 Image Classification of Mangrove Populations Change From Cyclone Amphan To Locate Communities in the Sundarbans Most Affected

Olivia Du Zhang, Age: 17
Kent Place School, New Jersey
Project Title: Adipocyte-Derived Extracellular Vesicles Reprogram Tumor Cells and Drive Stemness in Triple-Negative Breast Cancer

Serena Julissa Zhang, Age: 18
William G. Enloe High School, North Carolina
Project Title: Design and In Silico Validation of an Antigen-Conjugated Fc-Fusion Protein for the Treatment of Myasthenia Gravis

Shaohuan Zhang, Age: 18
Cranbrook Kingswood School, Michigan
Project Title: Generalizations of the Zesting Construction

Shuyue (Linda) Zhang, Age: 17
Scarsdale High School, New York
Project Title: Optimizing Gene Capture: A Direct Cloning Strategy for Large Genomic Fragments

Justin Zhao, Age: 19
Jericho Senior High School, New York
Project Title: Structural Insights Into the Hybrid Infection Strategy of Bacteriophage Peru-2

Max Zhao, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Improving Time-Series Flood Detection on Remote Sensing Satellite Imagery With Persistent Homology

Audrey Zheng, Age: 17
North Allegheny Senior High School, Pennsylvania
Project Title: Targeted Isolation of Tumor-Derived Extracellular Vesicles Using a Cocktail of Magnetic Nanospheres for Minimally Invasive Pancreatic Cancer Diagnosis

Lin Zheng, Age: 18
University School of Nashville, Tennessee
Project Title: Sex Differences in GABA-A Receptor Regulation of Dopamine Release in the Nucleus Accumbens and Its Role in Cocaine Use Disorder

Aiden Ruipeng Zhou, Age: 17
Western Academy of Beijing, China
Project Title: Flow Matching-Based Text-to-Speech for Low-Resource Automatic Speech Recognition Augmentation

Eric Zhou, Age: 18
Troy High School, Michigan
Project Title: Adaptive DAG-Based BFT Consensus Protocols Using Machine Learning

Liran Zhou, Age: 17
Jericho Senior High School, New York
Project Title: Novel Reconfigurable Straight-Spoke Triwheel Mechanism With Four-Bar Linkage for Optimal Stair Climbing

Bryan Zhu, Age: 18
Bellevue High School, WA
Project Title: Dimension Reduction for Smooth Convex Optimization via Color Refinement

Elena Tao Zhu, Age: 18
Upper Arlington High School, Ohio
Project Title: Intracellular Calcium Oscillation Promotes the Migration and Invasion of Liposarcoma Cells